Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210134 | 0.85 | HPGD (0.44) | L3MBTL1SMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL14141727 | 0.83 | CYP19A1 (0.42) | MAPTTSHRKMT2AALDH1A1TP53 | |
| SCHEMBL29777919 | 0.82 | TSHR (0.52) | L3MBTL1SMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL8239082 | 0.82 | TSHR (0.52) | L3MBTL1SMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL26849710 | 0.82 | L3MBTL1 (0.40) | L3MBTL1SMN1; SMN2MAPTTSHRHSP90AB1 | |
| SCHEMBL936740 | 0.80 | HTT (0.47) | MAPTTSHRKMT2AALDH1A1TP53 | |
| SCHEMBL13990159 | 0.80 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2MAPTTSHRHSP90AB1 | |
| SCHEMBL2356747 | 0.79 | ALDH1A1 (0.49) | MAPTTSHRKMT2AALDH1A1TP53 | |
| SCHEMBL10787348 | 0.79 | ALDH1A1 (0.49) | MAPTTSHRKMT2AALDH1A1TP53 | |
| SCHEMBL7999608 | 0.79 | ALDH1A1 (0.49) | MAPTTSHRKMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| EP-4132559-A1 | MODIFIED KISSPEPTIN RECEPTOR AGONISTS FOR FATTY LIVER DISEASE | Rutgers, the State University of New Jersey (US) | 2023-02-15 | — | — | EP | disclosed |
| US-20210128561-A1 | MRGX Receptor Antagonists | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2021-05-06 | — | — | US | disclosed |
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1797082-B1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| CN-101133108-B | Cellulose acylate film, polarizing plate and liquid crystal display device | FUJIFILM CORP. (JP) | 2011-12-07 | — | — | CN | disclosed |
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
| EP-2303884-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2011-04-06 | — | — | EP | disclosed |
| CN-1288909-A | Use of polymer coating for rubber products | NAT STARCH CHEM INVEST (US) | 2001-03-28 | — | — | CN | disclosed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | disclosed |
| CN-1231005-A | Process for improving polyamide, acrylic, aramid, cellulosic and polyester properties, and modified polymers produced thereby | INTERA TECHNOLOGIES INC (US) | 1999-10-06 | — | — | CN | disclosed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |
| CN-1185162-A | Acrylic polymer composition | ICI PLC (GB) | 1998-06-17 | — | — | CN | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4975349-A | Bonded to an aromatic hydrocarbon group on an electroconductive substrate | CANON KABUSHIKI KAISHA (JP) | 1990-12-04 | — | — | US | disclosed |
| WO-1989004305-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |
| EP-0315399-A2 | Quinoline derivatives, their use in the treatment of hypersensitive ailments and a pharmaceutical composition containing the same | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1989-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | ADORA2A, ADORA1, ADORA3 | L3MBTL1 2483/4885SMN1; SMN2 897/4885MAPT 2289/4885 |
| US-20210128561-A1 | MRGX Receptor Antagonists | MRGPRX2, MRGPRX1, MRGPRX4 | L3MBTL1 4197/4885SMN1; SMN2 1481/4885MAPT 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.