Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 11/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568392 | 0.81 | CYP1A2 (0.44) | — | |
| SCHEMBL24268206 | 0.75 | ADA (0.53) | ADAKDM5A | |
| SCHEMBL10959131 | 0.75 | CA5A (0.52) | CA5ACES2CES1 | |
| SCHEMBL30582304 | 0.72 | CA5A (0.48) | ADACA5ASCN9ACES2CES1 | |
| SCHEMBL27781574 | 0.70 | ADA (0.51) | ADAKDM5A | |
| SCHEMBL9714477 | 0.69 | ALDH1A1 (0.49) | CES2CES1 | |
| SCHEMBL9714146 | 0.69 | CA5A (0.58) | ADACA5AKDM5AKDM5B | |
| SCHEMBL4981212 | 0.68 | ADA (0.55) | ADA | |
| SCHEMBL30582364 | 0.68 | ADA (0.43) | ADACA5A | |
| SCHEMBL7452973 | 0.67 | ADA (0.48) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248414-B1 | ARALKYL IMIDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-23 | — | — | EP | claimed |
| EP-0248414-A2 | Aralkyl imidazole derivatives | CIBA-GEIGY AG (CH) | 1987-12-09 | — | — | EP | claimed |
| EP-0248414-B1 | ARALKYL IMIDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-23 | — | — | EP | disclosed |
| US-4851424-A | 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0248414-A2 | Aralkyl imidazole derivatives | CIBA-GEIGY AG (CH) | 1987-12-09 | — | — | EP | disclosed |