Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20971369 | 0.81 | GABRB2 (0.55) | CYP1A2NOTUMGAANPC1RAB9A | |
| SCHEMBL18316510 | 0.81 | GABRB2 (0.55) | CYP1A2NOTUMGAANPC1RAB9A | |
| SCHEMBL29215821 | 0.81 | GABRB2 (0.55) | CYP1A2NOTUMGAANPC1RAB9A | |
| SCHEMBL9714322 | 0.81 | ADA (0.48) | — | |
| SCHEMBL12458255 | 0.79 | NOTUM (0.49) | CYP1A2NOTUMGAAGABRB2GABRA2 | |
| SCHEMBL28934812 | 0.78 | GAA (0.47) | CYP1A2NOTUMGAASMN1; SMN2NPC1 | |
| SCHEMBL28934814 | 0.78 | GAA (0.47) | CYP1A2NOTUMGAASMN1; SMN2NPC1 | |
| SCHEMBL10669079 | 0.78 | ALDH1A1 (0.48) | CYP1A2GAASMN1; SMN2TP53GABRB2 | |
| SCHEMBL28934718 | 0.78 | GABRA1 (0.45) | CYP1A2NOTUMGAAGABRB2GABRA2 | |
| SCHEMBL28934720 | 0.78 | GABRA1 (0.45) | CYP1A2NOTUMGAAGABRB2GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851424-A | 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |