Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714658 | 0.91 | PPARG (0.44) | ALDH1A1ALOX5PPARGPPARAPTGES | |
| SCHEMBL28567055 | 0.80 | TSHR (0.44) | ALDH1A1ALOX5PPARGPPARAPTGES | |
| SCHEMBL3836107 | 0.77 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1ALOX5NAMPT | |
| SCHEMBL8856146 | 0.77 | PPARG (0.52) | ALDH1A1ALOX5PPARGPPARAPTGES | |
| SCHEMBL7364397 | 0.76 | HDAC1 (0.57) | CYP4F2CYP4A11ALDH1A1NAMPTPTGDR2 | |
| SCHEMBL711239 | 0.76 | CYP3A4 (0.52) | CYP4F2CYP4A11ALDH1A1ALOX5PPARG | |
| SCHEMBL9811164 | 0.76 | MAPT (0.53) | ALDH1A1PPARGPPARAKMT2A | |
| SCHEMBL6656240 | 0.76 | ALOX5 (0.49) | ALOX5PPARGPPARAPTGES | |
| SCHEMBL17785156 | 0.75 | PIN1 (0.42) | ALDH1A1ALOX5PPARGPPARACYP2C19 | |
| SCHEMBL433489 | 0.75 | LMNA (0.51) | CYP4F2CYP4A11ALDH1A1ALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166369-A | Precursors and synthesis of D1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates | AMERICAN CYANAMID COMPANY | 1992-11-24 | — | — | US | disclosed |
| US-4983753-A | Precursors and synthesis of di-(methyl)-16,16-(dimethyl)-11-alpha,15-alpha beta-dihydroxy-9-oxo-2,13-trans,trans-prostadienoates | FLOYD JR MIDDLETON B (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0065638-B1 | SUBSTITUTED 7-(4-SUBSTITUTED-CYCLOPENT-2-EN-1-ON-2-YL)-HEPT-2-TRANSENOATES | AMERICAN CYANAMID COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4644079-A | Precursors and synthesis of d1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1987-02-17 | — | — | US | disclosed |
| US-4474979-A | Synthesis of d1-(methyl)-16,16-(dimethyl-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans,trans-prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0065638-A1 | Substituted 7-(4-substituted-cyclopent-2-en-1-on-2-yl)-hept-2-transenoates | AMERICAN CYANAMID COMPANY (US) | 1982-12-01 | — | — | EP | disclosed |
| US-4360688-A | Precursors and synthesis of d1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4254036-A | 1-Hydroxymethyl-1-oxo-prostane-derivatives of the E, A and F-series | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| EP-0015056-A1 | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E, A and F series | AMERICAN CYANAMID COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |