Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714669 | 0.88 | LTA4H (0.41) | LTA4HMAPK1KIF11ACSS2MAPT | |
| SCHEMBL9560742 | 0.83 | LTA4H (0.40) | LTA4HMAPK1KIF11ACSS2MAPT | |
| SCHEMBL9714388 | 0.81 | LTA4H (0.45) | LTA4HMAPK1MAPTL3MBTL1LMNA | |
| SCHEMBL10551981 | 0.78 | LTA4H (0.46) | LTA4HMAPK1MAPTL3MBTL1LMNA | |
| SCHEMBL9714593 | 0.78 | LTA4H (0.41) | LTA4HMAPK1KIF11MAPTL3MBTL1 | |
| SCHEMBL9560672 | 0.74 | LTA4H (0.42) | LTA4HMAPK1KIF11MAPTL3MBTL1 | |
| SCHEMBL9747164 | 0.73 | LTA4H (0.41) | LTA4HMAPK1KIF11MAPTL3MBTL1 | |
| SCHEMBL9560684 | 0.73 | LTA4H (0.40) | LTA4HMAPK1KIF11MAPTL3MBTL1 | |
| SCHEMBL9714661 | 0.72 | LTA4H (0.39) | LTA4HMAPK1KIF11MAPTL3MBTL1 | |
| SCHEMBL9714162 | 0.72 | LTA4H (0.39) | LTA4HMAPK1KIF11MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273549-B1 | INSECTICIDAL THIOETHERS AND DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5068461-A | 1,1,1-trifluoro-2-(4-alkoxyphenyl)prop-2-ene compounds for aphids, mites and other insects | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | disclosed |
| US-4937388-A | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0273549-A1 | Insecticidal thioethers and derivatives thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-06 | — | — | EP | disclosed |