Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554877 | 0.86 | LOXL2 (0.37) | KDM4EHPGDKCNH2L3MBTL1MAPT | |
| SCHEMBL10557151 | 0.86 | L3MBTL1 (0.35) | SMN1; SMN2NPC1RAB9AHPGDKCNH2 | |
| SCHEMBL8858271 | 0.81 | LTA4H (0.46) | LTA4HSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9714669 | 0.79 | LTA4H (0.41) | LTA4HSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL9714593 | 0.79 | LTA4H (0.41) | LTA4HSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL10554911 | 0.79 | LTA4H (0.51) | LTA4HSMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL9714640 | 0.78 | LTA4H (0.39) | LTA4HKDM4EL3MBTL1MAPK1MAPT | |
| SCHEMBL9198043 | 0.70 | KCNH2 (0.44) | LTA4HSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9335440 | 0.70 | LTA4H (0.46) | LTA4HSMN1; SMN2RAB9AKCNH2RELA | |
| SCHEMBL10549191 | 0.69 | LTA4H (0.44) | LTA4HSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804653-A | INSECTICIDES, MITICIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1989-02-14 | — | — | US | claimed |
| US-4804653-A | INSECTICIDES, MITICIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1989-02-14 | — | — | US | disclosed |