Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714706 | 0.84 | MAOA (0.34) | MAOBMAOACYP3A4TDP1TSHR | |
| SCHEMBL9714810 | 0.80 | ENPP2 (0.42) | MAOBATMMEN1KMT2ACYP3A4 | |
| SCHEMBL11252427 | 0.75 | MAOB (0.65) | MAOBATMMAOAMEN1KMT2A | |
| SCHEMBL11252440 | 0.75 | MAOB (0.65) | MAOBATMMAOAMEN1KMT2A | |
| SCHEMBL9714736 | 0.74 | MAOA (0.42) | MAOBMAOACYP3A4TDP1TSHR | |
| SCHEMBL9714573 | 0.74 | MEN1 (0.34) | MAOBMAOAMEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL9714744 | 0.71 | MAOB (0.38) | MAOBATMMAOAMEN1KMT2A | |
| SCHEMBL9714816 | 0.71 | SLC6A2 (0.34) | MAOBATMMAOAMEN1KMT2A | |
| (Chloromethyl)Benzene SCHEMBL304085 | 0.70 | CYP3A4 (0.60) | MEN1KMT2ACYP3A4TDP1TSHR | |
| SCHEMBL9714785 | 0.69 | CTSB (0.35) | ATMCYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166210-A | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-11-24 | — | — | US | disclosed |