Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714958 | 0.90 | SMN1; SMN2 (0.46) | RAB9AHTTMAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL9739282 | 0.89 | HTT (0.57) | RAB9AHTTMAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL9714945 | 0.88 | HSD17B10 (0.46) | POLBHTTMAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL9715038 | 0.84 | L3MBTL1 (0.43) | RAB9APOLBSMN1; SMN2ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9714943 | 0.84 | L3MBTL1 (0.45) | RAB9APOLBSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9714952 | 0.83 | LMNA (0.45) | RAB9APOLBALDH1A1L3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL9715094 | 0.75 | LMNA (0.53) | RAB9APOLBHTTMAPK10SMN1; SMN2 | |
| SCHEMBL20075139 | 0.74 | IKBKB (0.50) | HTTMAPK10SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9714924 | 0.74 | HSD17B10 (0.41) | HTTMAPK10SMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9714991 | 0.73 | HSD17B10 (0.40) | HTTMAPK10SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | claimed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |