Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9714991 | 0.99 | HSD17B10 (0.40) | HSD17B10KDM4EALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL9715038 | 0.90 | L3MBTL1 (0.43) | HSD17B10KDM4EALDH1A1CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL9714943 | 0.89 | L3MBTL1 (0.45) | HSD17B10KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL9714958 | 0.84 | SMN1; SMN2 (0.46) | HSD17B10KDM4EALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL9715049 | 0.81 | RAB9A (0.54) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9714916 | 0.78 | LMNA (0.41) | HSD17B10KDM4ECYP3A4HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9714930 | 0.78 | LMNA (0.41) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9714927 | 0.74 | RAB9A (0.44) | HSD17B10KDM4EALDH1A1SMN1; SMN2ALPL | |
| SCHEMBL9739282 | 0.74 | HTT (0.57) | HSD17B10KDM4EALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL9714945 | 0.74 | HSD17B10 (0.46) | HSD17B10KDM4EALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | claimed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | claimed |