Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714958 | 0.90 | SMN1; SMN2 (0.46) | HTTMAPK10SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9714927 | 0.89 | RAB9A (0.44) | HTTMAPK10SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9714945 | 0.88 | HSD17B10 (0.46) | HTTMAPK10SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4208809 | 0.79 | HTT (0.59) | HTTMAPK10SMN1; SMN2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9715094 | 0.75 | LMNA (0.53) | HTTMAPK10SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9714924 | 0.74 | HSD17B10 (0.41) | HTTMAPK10SMN1; SMN2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9714991 | 0.73 | HSD17B10 (0.40) | HTTMAPK10SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9715038 | 0.73 | L3MBTL1 (0.43) | SMN1; SMN2ALDH1A1KDM4EPTGS2RAB9A | |
| Hydrochloric Acid SCHEMBL9714943 | 0.73 | L3MBTL1 (0.45) | SMN1; SMN2ALDH1A1KDM4EPTGS2RAB9A | |
| SCHEMBL9714952 | 0.72 | LMNA (0.45) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |