Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563398 | 0.85 | AKR1C3 (0.54) | NPC1RAB9AAKR1C3MAPTLMNA | |
| SCHEMBL9715111 | 0.82 | AKR1C3 (0.53) | NPC1RAB9AAKR1C3MAPTLMNA | |
| SCHEMBL9715106 | 0.82 | AKR1C3 (0.53) | NPC1RAB9AAKR1C3MAPTLMNA | |
| SCHEMBL1921185 | 0.81 | F2RL1 (0.62) | NPC1RAB9APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL1237225 | 0.80 | AKR1C3 (0.62) | AKR1C3MAPTALDH1A1ATM | |
| SCHEMBL20500020 | 0.80 | AKR1C3 (0.62) | AKR1C3MAPTALDH1A1ATM | |
| SCHEMBL1237224 | 0.80 | AKR1C3 (0.62) | AKR1C3MAPTALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL9445568 | 0.78 | AKR1C3 (0.60) | AKR1C3MAPTALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL9445569 | 0.78 | AKR1C3 (0.60) | AKR1C3MAPTALDH1A1ATM | |
| SCHEMBL1790765 | 0.78 | RAB9A (0.44) | NPC1RAB9AAKR1C3MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297285-B1 | COMPATIBLE BLENDS OF POLYCARBONATE AND POLYMETHACRYLATE | RÖHM GMBH (DE) | 1992-10-14 | — | — | EP | disclosed |
| EP-0297285-A2 | Compatible blends of polycarbonate and polymethacrylate | Röhm GmbH (DE) | 1989-01-04 | — | — | EP | disclosed |