SCHEMBL2563398

SCHEMBL2563398

C=C(CCc1ccccc1)C(=O)O.CC(=Cc1ccc(C)cc1)C(=O)O.CC(=Cc1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.54
ALDH1A1 P00352 3/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
TBXAS1 P24557 2/20 0.43
PLAAT3 P53816 1/20 0.41
PLAAT5 Q96KN8 1/20 0.41
PLAAT2 Q9NWW9 1/20 0.41
PLAAT4 Q9UL19 1/20 0.41
MAPT P10636 2/20 0.41
POLB P06746 1/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
GPR52 Q9Y2T5 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715109 0.85 NPC1 (0.52) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL16445337 0.79 AKR1C3 (0.44) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL1921016 0.79 FFAR1 (0.54) ALDH1A1L3MBTL1TDP1PLAAT3PLAAT5
Styrene SCHEMBL14801675 0.78 ALDH1A1 (0.50) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
Methacrylic Acid SCHEMBL1082311 0.77 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL16395701 0.77 AKR1C3 (0.62) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL474138 0.77 AKR1C3 (0.69) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9956060 0.77 AKR1C3 (0.69) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL1920235 0.77 AKR1C3 (0.69) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL30529 0.77 KEAP1 (0.61) ALDH1A1NPC1RAB9ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1586605-B1 POLYMER AND CURABLE COMPOSITIONS IMPROVED IN STORAGE STABILITY KANEKA CORP (JP) 2011-11-02 EP disclosed