SCHEMBL1790765

SCHEMBL1790765

C=C(CCC(C)=Cc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
THRB P10828 2/20 0.44
ATM Q13315 1/20 0.44
GSK3B P49841 2/20 0.43
AKR1C3 P42330 1/20 0.43
MAPT P10636 5/20 0.42
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
F3 P13726 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
APEX1 P27695 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PPARA Q07869 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1787701 0.84 RAB9A (0.43) RAB9ANPC1THRBATMGSK3B
SCHEMBL1789290 0.83 AKR1C3 (0.52) AKR1C3KDM4EALDH1A1CYP3A4TSHR
SCHEMBL1791239 0.82 AKR1C3 (0.36) RAB9ANPC1AKR1C3KDM4EALDH1A1
SCHEMBL1793881 0.82 CYP2C9 (0.46) AKR1C3KDM4EALDH1A1CYP1A2PPARA
SCHEMBL8144362 0.78 ALDH1A1 (0.50) RAB9ANPC1THRBATMGSK3B
SCHEMBL9715109 0.78 NPC1 (0.52) RAB9ANPC1ATMAKR1C3MAPT
SCHEMBL1789109 0.77 MEN1 (0.45) RAB9ANPC1ATMMAPTKDM4E
SCHEMBL1354040 0.77 MAPT (0.45) RAB9ANPC1THRBATMGSK3B
SCHEMBL1790768 0.77 THRB (0.51) RAB9ANPC1THRBATMGSK3B
SCHEMBL29120646 0.76 GSK3B (0.53) RAB9ANPC1THRBATMGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS RAB9A 4200/4885NPC1 4759/4885THRB 1303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.