Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103700 | 0.86 | ADRB1 (0.74) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10373770 | 0.86 | ADRB1 (0.74) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL28661128 | 0.86 | ADRB1 (0.53) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL8264176 | 0.82 | ADRB1 (0.69) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL12991 | 0.82 | ADRB1 (0.69) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL30461168 | 0.81 | KCNH2 (0.51) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL17281442 | 0.80 | ADRB1 (0.67) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL3307690 | 0.80 | ADRB1 (0.67) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11096302 | 0.80 | KCNH2 (0.73) | ADRB1KCNH2MAPTALDH1A1RAB9A | |
| SCHEMBL15507872 | 0.80 | ADRB1 (0.61) | ADRB1KCNH2L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308961-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5021412-A | Protecting agricultural crops | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0308961-A1 | Thiadiazines, process for production thereof, and insecticide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-03-29 | — | — | EP | disclosed |