Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803850 | 0.81 | NPC1 (0.49) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL8519976 | 0.78 | RAB9A (0.47) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL4255052 | 0.75 | NPC1 (0.53) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL8219151 | 0.71 | ACKR3 (0.41) | RAB9ALMNAALDH1A1ACKR3 | |
| SCHEMBL9250759 | 0.69 | RAB9A (0.61) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL1245893 | 0.66 | RAB9A (0.57) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL4809812 | 0.66 | RAB9A (0.57) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL19359519 | 0.66 | RAB9A (0.57) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL19359518 | 0.66 | RAB9A (0.57) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL19380827 | 0.66 | RAB9A (0.57) | NPC1RAB9APKMPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017333-A1 | SELF-ASSEMBLED SUPER LATTICES | NORTHWESTERN UNIVERSITY (US) | 1992-10-15 | — | — | WO | disclosed |