Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | IGF2R | P11717 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803850 | 0.82 | NPC1 (0.49) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL4809812 | 0.77 | RAB9A (0.57) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL11993126 | 0.77 | RAB9A (0.57) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL8519976 | 0.76 | RAB9A (0.47) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL24412896 | 0.76 | ALDH1A1 (0.47) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL20509577 | 0.76 | ALDH1A1 (0.47) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL9250759 | 0.76 | RAB9A (0.61) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL9715375 | 0.75 | NPC1 (0.46) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL28363283 | 0.74 | MAPT (0.46) | NPC1RAB9APKMPOLBALDH1A1 | |
| SCHEMBL305384 | 0.74 | CYP19A1 (0.50) | ALDH1A1KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814854-A4 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC FOUND FOR RES DEV (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1814854-A1 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC Foundation For Research Development (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006050264-A1 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2006-05-11 | — | — | WO | disclosed |
| US-5834230-A | Viscosity Probe | MCGILL UNIVERSITY (CA) | 1998-11-10 | — | — | US | disclosed |
| US-4987056-A | IMPROVED SENSITIVITY TO VISIBLE LIGHT | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-01-22 | — | — | US | disclosed |