Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP16 | P51512 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600925 | 0.85 | GABRA1 (0.41) | PTGS1CLCN2 | |
| SCHEMBL9715714 | 0.84 | ALDH1A1 (0.47) | CXCL8PTGS2PTGS1MMP2MMP9 | |
| SCHEMBL9715755 | 0.83 | PTGS2 (0.44) | CXCL8PTGS2PTGS1MMP2MMP9 | |
| SCHEMBL9715715 | 0.82 | HCRTR1 (0.48) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL9632497 | 0.82 | PTGS2 (0.47) | CXCL8PTGS2PTGS1MMP2MMP9 | |
| SCHEMBL9715744 | 0.81 | TSHR (0.57) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL30222272 | 0.81 | PTGS2 (0.46) | CXCL8PTGS2PTGS1MMP2MMP9 | |
| SCHEMBL5112475 | 0.81 | PTGS2 (0.46) | CXCL8PTGS2PTGS1MMP2MMP9 | |
| SCHEMBL5983552 | 0.81 | PTGS2 (0.46) | CXCL8PTGS2PTGS1MMP2MMP9 | |
| SCHEMBL9715759 | 0.80 | TSHR (0.45) | CXCL8PTGS2PTGS1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304495-B1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4908473-A | Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0304495-A1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-03-01 | — | — | EP | disclosed |