Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439694 | 0.89 | TSHR (0.52) | TSHRLMNAALDH1A1CFTRHSD17B10 | |
| SCHEMBL9715751 | 0.89 | PTGS1 (0.42) | TSHRLMNAALDH1A1CFTRHSD17B10 | |
| SCHEMBL9715744 | 0.86 | TSHR (0.57) | TSHRALDH1A1HSD17B10PTGS1PTGS2 | |
| SCHEMBL9715714 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HSD17B10MAPTALOX15PTGS1 | |
| SCHEMBL9715754 | 0.82 | PTGS1 (0.52) | ALDH1A1HSD17B10PTGS1PTGS2KDM4E | |
| SCHEMBL9715755 | 0.81 | PTGS2 (0.44) | TSHRLMNAALDH1A1HSD17B10MAPT | |
| SCHEMBL9632497 | 0.81 | PTGS2 (0.47) | LMNAALDH1A1HSD17B10MAPTPTGS1 | |
| SCHEMBL9717379 | 0.81 | KDM4E (0.45) | TSHRLMNAALDH1A1CFTRHSD17B10 | |
| SCHEMBL9715718 | 0.80 | CXCL8 (0.41) | ALDH1A1PTGS1PTGS2POLBCXCL8 | |
| SCHEMBL9715715 | 0.78 | HCRTR1 (0.48) | LMNAALDH1A1MAPTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304495-B1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4908473-A | Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0304495-A1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-03-01 | — | — | EP | disclosed |