Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | CD74 | P04233 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716028 | 0.89 | MIF (0.57) | MIFALDH1A1CD74POLBKMT2A | |
| SCHEMBL9715990 | 0.83 | NPC1 (0.57) | MIFALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL9716002 | 0.83 | MIF (0.44) | MIFPTGS2CD74POLBKMT2A | |
| SCHEMBL536309 | 0.83 | TDP1 (0.47) | MIFALDH1A1POLBKMT2ARAB9A | |
| SCHEMBL9716054 | 0.82 | MIF (0.46) | MIFALDH1A1CD74POLBKMT2A | |
| SCHEMBL9716010 | 0.82 | MET (0.51) | MIFALDH1A1CD74POLBKMT2A | |
| SCHEMBL9715968 | 0.80 | CA12 (0.47) | ALDH1A1KMT2AMEN1METRAB9A | |
| SCHEMBL9715963 | 0.80 | KMO (0.46) | MIFPOLBKMT2AMEN1LMNA | |
| SCHEMBL536696 | 0.79 | MAPK1 (0.62) | MIFALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL9715974 | 0.79 | IDO1 (0.47) | MIFKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102898-A | Halosubstituted alkyne group; fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-07 | — | — | US | disclosed |