Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPX4 | P36969 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992392 | 0.87 | MTNR1A (0.43) | MTNR1AMTNR1BHSD17B1HSD17B2MEN1 | |
| SCHEMBL8767879 | 0.85 | RAD52 (0.46) | MTNR1AMTNR1BHSD17B1HSD17B2HTR7 | |
| SCHEMBL11670936 | 0.84 | MTNR1A (0.47) | MTNR1AMTNR1BHSD17B1HSD17B2HTR7 | |
| SCHEMBL11519483 | 0.83 | GFER (0.49) | MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL28648224 | 0.83 | MTNR1A (0.43) | MTNR1AMTNR1BHSD17B1HSD17B2HTR7 | |
| SCHEMBL13164572 | 0.80 | HTR7 (0.45) | MTNR1AMTNR1BHSD17B1HSD17B2HTR7 | |
| SCHEMBL11671824 | 0.79 | LMNA (0.47) | MTNR1AMTNR1BHSD17B1HSD17B2MEN1 | |
| SCHEMBL9648292 | 0.76 | MTNR1A (0.48) | MTNR1AMTNR1BHSD17B1HSD17B2HTR7 | |
| SCHEMBL22400033 | 0.76 | HSD17B1 (0.43) | MTNR1AMTNR1BHSD17B1HSD17B2MEN1 | |
| SCHEMBL11138993 | 0.76 | HTR7 (0.51) | HSD17B1HSD17B2MEN1KMT2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101021-A | Disperse dyes for polyesters | SANDOZ LTD. (CH) | 1992-03-31 | — | — | US | disclosed |