Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18677528 | 0.89 | TDP1 (0.55) | TDP1MAPTPTGS2TPMTHSD17B10 | |
| SCHEMBL670626 | 0.87 | TPMT (0.49) | TDP1MAPTPTGS2TPMTHSD17B10 | |
| SCHEMBL159393 | 0.84 | MAPT (0.54) | TDP1MAPTPTGS2TPMTHSD17B10 | |
| SCHEMBL25378470 | 0.81 | TPMT (0.47) | TDP1MAPTPTGS2TPMTHSD17B10 | |
| SCHEMBL419090 | 0.81 | TDP1 (0.50) | TDP1MAPTPTGS2TPMTHSD17B10 | |
| Gallic Acid Methyl Ester SCHEMBL5334274 | 0.79 | LMNA (0.57) | TDP1MAPTPTGS2TPMTHSD17B10 | |
| Gallic Acid Methyl Ester SCHEMBL4604139 | 0.79 | LMNA (0.57) | TDP1MAPTPTGS2TPMTHSD17B10 | |
| SCHEMBL27731624 | 0.79 | HSD17B10 (0.52) | TDP1MAPTTPMTHSD17B10MEN1 | |
| SCHEMBL2456581 | 0.78 | CSNK2A1 (0.47) | TDP1MAPTPTGS2HSD17B10MEN1 | |
| SCHEMBL39512 | 0.78 | CSNK2A1 (0.47) | TDP1MAPTPTGS2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107261148-A | Methylphenidate prodrug, its preparation and application | 凯姆制药公司 | 2017-10-20 | — | — | CN | claimed |
| CN-106999486-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxycodone | 凯姆制药公司 | 2017-08-01 | — | — | CN | claimed |
| CN-106999487-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxymorphone, its prodrug, preparation and application | 凯姆制药公司 | 2017-08-01 | — | — | CN | claimed |
| CN-111333662-A | 3,4' -O-dimethyl gallic acid, its derivative and pharmaceutical use thereof | 西南医科大学 | 2020-06-26 | — | — | CN | disclosed |
| CN-107261148-A | Methylphenidate prodrug, its preparation and application | 凯姆制药公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-106999487-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxymorphone, its prodrug, preparation and application | 凯姆制药公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106999486-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxycodone | 凯姆制药公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-103826633-B | Methylphenidate prodrugs, methods of making and using the same | 凯姆制药公司 | 2017-05-24 | — | — | CN | disclosed |
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. | 2012-12-20 | — | — | US | disclosed |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | LIU DAKAI | 2010-11-25 | — | — | US | disclosed |
| US-5155111-A | Combined with 6-mercaptopurine | INSTITUTE OF MATERIA MEDICA (CN) | 1992-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | TDP1 4794/4885MAPT 3092/4885PTGS2 4205/4885 |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | TDP1 4794/4885MAPT 3092/4885PTGS2 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.