SCHEMBL9716586

SCHEMBL9716586

CO[Si](CCCc1ccccc1)(CCCc1ccccc1)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
IDO1 P14902 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SIGMAR1 Q99720 4/20 0.43
CHRM2 P08172 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CHRM1 P11229 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KCNH2 Q12809 1/20 0.42
AOC3 Q16853 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29040556 0.90 MAOA (0.44) MAOAIDO1L3MBTL1MEN1KMT2A
SCHEMBL9716603 0.87 TDP1 (0.46) IDO1KCNH2HTR2A
SCHEMBL6907531 0.83 KDM4E (0.38) MAOAIDO1L3MBTL1SIGMAR1
SCHEMBL2822247 0.83 IDO1 (0.45) MAOAIDO1L3MBTL1MEN1KMT2A
SCHEMBL3342170 0.82 IDO1 (0.44) MAOAIDO1L3MBTL1MEN1KMT2A
SCHEMBL1068905 0.82 IDO1 (0.44) MAOAIDO1L3MBTL1MEN1KMT2A
SCHEMBL964087 0.81 MAOA (0.47) MAOAL3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL19549542 0.81 SIGMAR1 (0.42) KMT2ASIGMAR1HTR2A
SCHEMBL4058172 0.80 IDO1 (0.42) MAOAIDO1L3MBTL1MEN1KMT2A
SCHEMBL4058177 0.80 IDO1 (0.42) MAOAIDO1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed