SCHEMBL6907531

SCHEMBL6907531

CO[Si](CCCS)(CCc1ccccc1)OC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
MAOA P21397 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
IDO1 P14902 2/20 0.35
ALDH1A1 P00352 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716603 0.87 TDP1 (0.46) KDM4ELMNATAAR1TDP1IDO1
SCHEMBL8150234 0.84 IDO1 (0.35) MAOATAAR1SIGMAR1IDO1ALDH1A1
SCHEMBL9716586 0.83 MAOA (0.48) MAOASIGMAR1IDO1L3MBTL1
SCHEMBL27353080 0.78 TDP1 (0.41) KDM4ELMNATAAR1TDP1IDO1
SCHEMBL9716575 0.78 TDP1 (0.41) KDM4ELMNATAAR1TDP1ALDH1A1
SCHEMBL3672253 0.77
SCHEMBL14015584 0.77 TDP1 (0.50) KDM4ELMNATAAR1TDP1ALDH1A1
SCHEMBL4075450 0.77 ALDH1A1 (0.46) KDM4ELMNATAAR1TDP1ALDH1A1
SCHEMBL4074034 0.77 TDP1 (0.40) KDM4ELMNATAAR1TDP1ALDH1A1
SCHEMBL4076426 0.77 TDP1 (0.45) KDM4ELMNATAAR1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6743303-B2 CONTACTING METAL SURFACE WITH ADHESION PROMOTION FORMULATION COMPRISING SULFURIC ACID AND PHOSPHORIC ACID TO FORM A MICRO-ROUGHENED CONVERSION COATED METAL SURFACE, CONTACTING WITH AQUEOUS ORGANOSILICON FORMULATION SHIPLEY COMPANY, L.L.C. 2004-06-01 US disclosed
US-20020132056-A1 Contacting metal surface with adhesion promotion formulation comprising sulfuric acid and phosphoric acid to form a micro-roughened conversion coated metal surface, contacting with aqueous organosilicon formulation SHIPLEY COMPANY, L.L.C. (US) 2002-09-19 US disclosed
EP-1016668-A2 Process for preparing silylalkylthiols Degussa-Hüls Aktiengesellschaft (DE) 2000-07-05 EP disclosed
EP-0471164-B1 Process for the preparation of mercaptosilanes HUELS CHEMISCHE WERKE AG (DE) 1995-11-15 EP disclosed
US-5107009-A PROCESS FOR THE PREPARATION OF MERCAPTOSILANES HULS AKTIENGESELLSCHAFT (DE) 1992-04-21 US disclosed
EP-0471164-A1 Process for the preparation of mercaptosilanes HÜLS AKTIENGESELLSCHAFT (DE) 1992-02-19 EP disclosed