Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661402 | 0.93 | ALDH1A1 (0.60) | ADRA2CALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL3656192 | 0.93 | ALDH1A1 (0.51) | ADRA2CALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL698882 | 0.89 | ADRA2C (0.64) | ADRA2CALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10660695 | 0.85 | BACE1 (0.52) | ADRA2CALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9716701 | 0.85 | ADRA2C (0.55) | ADRA2CALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6174036 | 0.85 | ADRA2C (0.51) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL6569544 | 0.85 | PKM (0.56) | ADRA2CALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11503381 | 0.82 | ADRA2C (0.49) | ADRA2CALDH1A1KMT2ANPC1PDK1 | |
| SCHEMBL11503382 | 0.82 | ADRA2C (0.49) | ADRA2CALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3659973 | 0.82 | TSHR (0.54) | ALDH1A1MEN1KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |