Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736663 | 0.79 | CA12 (0.50) | ESR2TTRHSD17B10KDM4EEGFR | |
| SCHEMBL10882055 | 0.79 | CA12 (0.46) | ESR1ESR2TTRKDM4EMEN1 | |
| SCHEMBL29038528 | 0.78 | HTT (0.59) | ESR1ESR2TTRHSD17B10KDM4E | |
| SCHEMBL9716693 | 0.76 | ESR1 (0.56) | ESR1ESR2TTRKDM4EEGFR | |
| SCHEMBL3040769 | 0.76 | HSD17B10 (0.58) | ESR1ESR2HSD17B10AKR1C3AKR1C2 | |
| SCHEMBL5667821 | 0.75 | RXRA (0.41) | TTRKDM4ERXRARXRBRXRG | |
| SCHEMBL9807221 | 0.75 | TTR (0.53) | ESR1ESR2TTRCA12CA1 | |
| SCHEMBL649980 | 0.75 | TTR (0.66) | TTRAKR1C3KDM4E | |
| SCHEMBL11121852 | 0.74 | HTT (0.51) | ESR1ESR2HSD17B10KDM4EMEN1 | |
| SCHEMBL9857403 | 0.74 | ESR2 (0.56) | ESR1ESR2HSD17B10EGFRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476471-A2 | High modulus polymeric composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |