Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915391 | 0.79 | TSHR (0.40) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL181776 | 0.76 | FDPS (0.35) | TSHRLMNA | |
| SCHEMBL975582 | 0.74 | FDPS (0.41) | TSHRCA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL31452970 | 0.74 | FDPS (0.33) | TSHRLMNA | |
| Isopropyl Alcohol SCHEMBL2245070 | 0.72 | TSHR (0.45) | TSHRCA1LMNA | |
| SCHEMBL29220683 | 0.70 | TSHR (0.39) | TSHRCA1LMNA | |
| SCHEMBL5052430 | 0.70 | TSHR (0.35) | TSHRLMNA | |
| SCHEMBL976818 | 0.70 | MMP1 (0.35) | CA12CA1CA2CA9LMNA | |
| SCHEMBL3462020 | 0.70 | OPRM1 (0.33) | — | |
| SCHEMBL28056858 | 0.70 | MAPT (0.39) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540565-A | The preparation of N, N (two) alkyl amino alkyl (methyl) acrylamide or corresponding ester and its quaternary ammonium salt | 赢创罗姆有限公司 | 2018-01-05 | — | — | CN | disclosed |
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4438235-A | POLYETHERS, POLYESTERS, POLYURETHANES | BASF WYANDOTTE CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |
| EP-0009154-B1 | COMPLEXES OF 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITIONS CONTAINING THE COMPLEXES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-12-08 | — | — | EP | disclosed |
| EP-0009155-B1 | 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITION CONTAINING THE 9-HYDROXYALKYL-PURINES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4221910-A | IMMUNOPOTENTIATORS, VIRICIDES, ANTILEUKEMIA AGENTS | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221909-A | P-Acetamidobenzoic acid salts of 9-(hydroxyalkyl) purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221794-A | Method of imparting immunomodulating and antiviral activity | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| EP-0009155-A1 | 9-Hydroxyalkyl-purines, processes for preparing them and therapeutical composition containing the 9-hydroxyalkyl-purines as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | disclosed |
| EP-0009154-A1 | Complexes of 9-hydroxyalkyl-purines, processes for preparing them and therapeutical compositions containing the complexes as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | disclosed |