Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.50 |
| ▸ | FPGS | Q05932 | 5/20 | 0.49 |
| ▸ | DHFR | P00374 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716814 | 1.00 | CA2 (0.54) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL9716816 | 1.00 | CA2 (0.54) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL9716715 | 0.95 | ERAP2 (0.55) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL9716710 | 0.95 | ERAP2 (0.55) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL31238118 | 0.91 | CA2 (0.56) | CA2CA1DHFR | |
| SCHEMBL10374327 | 0.88 | LNPEP (0.53) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL9716722 | 0.88 | ERAP2 (0.55) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL9716717 | 0.88 | ERAP2 (0.55) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL9716730 | 0.88 | ERAP2 (0.55) | CA2CA1ERAP2LNPEPERAP1 | |
| SCHEMBL1980150 | 0.88 | ITGB3 (0.57) | CA2CA1ERAP2LNPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |