Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717150 | 0.85 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9717130 | 0.85 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2028631 | 0.83 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL679847 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL19588493 | 0.80 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13129202 | 0.79 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL322653 | 0.78 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL63712 | 0.78 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11806965 | 0.77 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11805482 | 0.77 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861850-A | CONTACT LENSES | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1989-08-29 | — | — | US | claimed |
| US-5093447-A | Contact lenses | NOVICKY NICK N (CA) | 1992-03-03 | — | — | US | disclosed |
| US-4861850-A | CONTACT LENSES | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1989-08-29 | — | — | US | disclosed |
| US-4743106-A | POLYMER HAVING AN ORGANOSILOXANYLALKOXY ESTER OF (METH)ACRYLIC ACID MONOMER; MACHINING | Devou, Maureen J. (CA) | 1988-05-10 | — | — | US | disclosed |