SCHEMBL9717155

SCHEMBL9717155

O=C(Cl)CN1C(=O)c2c(Br)c(Br)c(Br)c(Br)c2C1=O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 5/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA7 P43166 3/20 0.40
CA12 O43570 3/20 0.40
CA4 P22748 2/20 0.35
GSK3B P49841 1/20 0.32
HIPK2 Q9H2X6 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172515 0.75 KDM4E (0.38) CA9CA1CA2CA7CA12
SCHEMBL10424654 0.73 BLM (0.43) CA9CA12
SCHEMBL7562782 0.73 CA9 (0.41) CA9CA1CA2CA7CA12
SCHEMBL6046957 0.72 CA9 (0.43) CA9CA1CA2CA7CA12
SCHEMBL29366486 0.72 CA9 (0.49) CA9CA1CA2CA7CA12
SCHEMBL94242 0.72 CA9 (0.49) CA9CA1CA2CA7CA12
SCHEMBL10998782 0.72 CA12 (0.37) CA9CA1CA2CA7CA12
SCHEMBL7468866 0.71 ALDH1A1 (0.48) CA9CA12GSK3BKDM4EALDH1A1
SCHEMBL8912698 0.70 CA9 (0.44) CA9CA1CA2CA7CA12
SCHEMBL5090368 0.69 CA12 (0.46) CA9CA1CA2CA7CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 US disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 EP disclosed