Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717764 | 0.82 | LMNA (0.38) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717761 | 0.81 | LMNA (0.37) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL31068449 | 0.79 | CA12 (0.44) | CFTRLMNACA12CA1CA2 | |
| SCHEMBL27922079 | 0.79 | CA12 (0.44) | CFTRLMNACA12CA1CA2 | |
| SCHEMBL28367227 | 0.78 | CA12 (0.40) | CFTRLMNAALDH1A1HSD17B10CA12 | |
| SCHEMBL5142275 | 0.78 | TPMT (0.42) | CFTRLMNAALDH1A1HSD17B10CA12 | |
| SCHEMBL11713096 | 0.76 | TSHR (0.41) | CFTRLMNAALDH1A1HSD17B10CA12 | |
| SCHEMBL29394151 | 0.76 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL6012587 | 0.76 | LMNA (0.40) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL124763 | 0.76 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003269-A1 | MICROSPHERES OF POLYHYDROXYLIC MATERIALS | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 1994-02-17 | — | — | WO | disclosed |