Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717818 | 0.86 | LMNA (0.50) | LMNACYP2C9CYP1A2CHRM1TBXA2R | |
| SCHEMBL10932897 | 0.77 | LMNA (0.43) | LMNACYP2C9CYP1A2CHRM1TBXA2R | |
| SCHEMBL9387753 | 0.72 | CFTR (0.41) | LMNACYP2C9CYP1A2CHRM1TBXA2R | |
| SCHEMBL11821639 | 0.70 | SERPINE1 (0.40) | LMNACYP2C9CYP1A2CHRM1TBXA2R | |
| SCHEMBL11572071 | 0.69 | SMN1; SMN2 (0.47) | LMNACHRM1TBXA2RPDE4AADRA1A | |
| SCHEMBL8726308 | 0.69 | LMNA (0.41) | LMNACYP1A2ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9717764 | 0.69 | LMNA (0.38) | LMNACYP2C9CYP1A2CHRM1TBXA2R | |
| SCHEMBL7749002 | 0.69 | LMNA (0.65) | LMNACYP2C9CYP1A2GAANPSR1 | |
| SCHEMBL9717912 | 0.68 | LMNA (0.41) | LMNACYP2C9CYP1A2CHRM1TBXA2R | |
| SCHEMBL12942245 | 0.67 | NR1H2 (0.45) | GAANPSR1ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233376-B1 | RADIOPAQUE THERMOPLASTIC RESIN-SILICONE NETWORK RESIN COMPOSITIONS AND MEDICAL-SURGICAL TUBINGS PREPARED THEREFROM | Becton, Dickinson and Company (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0233376-A1 | Radiopaque thermoplastic resin-silicone network resin compositions and medical-surgical tubings prepared therefrom | Becton, Dickinson and Company (US) | 1987-08-26 | — | — | EP | claimed |
| EP-0233376-B1 | RADIOPAQUE THERMOPLASTIC RESIN-SILICONE NETWORK RESIN COMPOSITIONS AND MEDICAL-SURGICAL TUBINGS PREPARED THEREFROM | Becton, Dickinson and Company (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0233376-A1 | Radiopaque thermoplastic resin-silicone network resin compositions and medical-surgical tubings prepared therefrom | Becton, Dickinson and Company (US) | 1987-08-26 | — | — | EP | disclosed |
| US-4557959-A | SOFTENER GRADIENT BETWEEN WALLS | REHAU PLASTIKS AG & CO. (DE) | 1985-12-10 | — | — | US | disclosed |
| EP-0086512-A2 | Laminated medical articles | REHAU AG + Co (DE) | 1983-08-24 | — | — | EP | disclosed |