Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932897 | 0.87 | LMNA (0.43) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717831 | 0.86 | LMNA (0.42) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9387753 | 0.74 | CFTR (0.41) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717912 | 0.72 | LMNA (0.41) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717766 | 0.72 | LMNA (0.39) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717764 | 0.71 | LMNA (0.38) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717761 | 0.70 | LMNA (0.37) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL124763 | 0.69 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL29394151 | 0.69 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL11821639 | 0.69 | SERPINE1 (0.40) | LMNACYP2C9CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233376-B1 | RADIOPAQUE THERMOPLASTIC RESIN-SILICONE NETWORK RESIN COMPOSITIONS AND MEDICAL-SURGICAL TUBINGS PREPARED THEREFROM | Becton, Dickinson and Company (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0233376-A1 | Radiopaque thermoplastic resin-silicone network resin compositions and medical-surgical tubings prepared therefrom | Becton, Dickinson and Company (US) | 1987-08-26 | — | — | EP | claimed |
| EP-0233376-B1 | RADIOPAQUE THERMOPLASTIC RESIN-SILICONE NETWORK RESIN COMPOSITIONS AND MEDICAL-SURGICAL TUBINGS PREPARED THEREFROM | Becton, Dickinson and Company (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0233376-A1 | Radiopaque thermoplastic resin-silicone network resin compositions and medical-surgical tubings prepared therefrom | Becton, Dickinson and Company (US) | 1987-08-26 | — | — | EP | disclosed |