SCHEMBL2004560

SCHEMBL2004560

Cc1cc(C(C)(c2ccccc2)c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.66
ESR2 Q92731 4/20 0.66
TTR P02766 1/20 0.48
ALOX5 P09917 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
CYTH2 Q99418 1/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ALOX15 P16050 1/20 0.40
PKM P14618 1/20 0.39
NPC1 O15118 1/20 0.39
MAPK1 P28482 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30899192 0.92 ESR2 (0.74) ESR1ESR2TTRALOX5PTGS1
SCHEMBL2618675 0.89 ESR1 (0.55) ESR1ESR2TTRALOX5PTGS1
SCHEMBL455094 0.86 CA2 (0.55) ESR1ESR2TTRALOX5PTGS1
SCHEMBL5086131 0.85 ESR1 (0.69) ESR1ESR2TTRALOX5PTGS1
SCHEMBL23861509 0.85 ESR2 (0.54) ESR1ESR2TTRALOX5PTGS1
SCHEMBL17273215 0.84 ESR1 (0.53) ESR1ESR2TTRALOX5PTGS1
SCHEMBL8349499 0.84 ESR1 (0.53) ESR1ESR2TTRALOX5PTGS1
SCHEMBL8407830 0.84 CA2 (0.52) ESR1ESR2TTRALOX5PTGS1
SCHEMBL23861357 0.83 ESR1 (0.60) ESR1ESR2ALDH1A1CYP3A4KMT2A
SCHEMBL13609942 0.83 ESR1 (0.59) ESR1ESR2ALDH1A1CYP3A4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671167-B2 Poly(arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-02 US claimed
US-20090247724-A1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-01 US claimed
EP-1969030-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2008-09-17 EP claimed
WO-2007067669-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO claimed
US-20070135609-A1 Poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-06-14 US claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
US-20260132242-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT DIC CORPORATION (JP) 2026-05-14 US disclosed
EP-3636692-B1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECH BV (NL) 2026-04-29 EP disclosed
US-12600856-B2 Resin composition, formed article, and, formed article with hard coat layer MITSUBISHI CHEMICAL CORPORATION (JP) 2026-04-14 US disclosed
US-20260071104-A1 Anionic Curable Compositions DESIGNER MOLECULES INC (US) 2026-03-12 US disclosed
US-20260071103-A1 Anionic Curable Compositions DESIGNER MOLECULES INC (US) 2026-03-12 US disclosed
US-12503593-B2 Curable thermosetting composition including poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-12-23 US disclosed
WO-2025224626-A1 THERMOPLASTIC POLYURETHANE AND ASSOCIATED METHOD AND ARTICLE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-10-30 WO disclosed
EP-0768155-A1 Process for making thermoplastic granules from polymer solutions BAYER AG (DE) 1997-04-16 EP disclosed
EP-0747749-A1 ELECTRODE PLATE FOR LIQUID CRYSTAL KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-12-11 EP disclosed
EP-0742260-A1 (Co)polycarbonates stabilized against gamma-rays BAYER AG (DE) 1996-11-13 EP disclosed
EP-0732365-A1 Polycarbonate compositions resistant to gamma radiation BAYER AG (DE) 1996-09-18 EP disclosed
EP-0402729-B1 Polycarbonates having vinylaromatic endgroup BAYER AG (DE) 1995-03-01 EP disclosed
EP-0500131-A2 Polycarbonate resin solution for film formation by casting MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-08-26 EP disclosed
US-4956485-A Trialkylsilyloxy-1,1-diphenyl ethylenes and polymers produced therewith BAYER AKTIENGESELLSCHAFT (DE) 1990-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071104-A1 Anionic Curable Compositions VCL, ITGA8, GABRE ESR1 467/4885ESR2 1403/4885TTR 2823/4885
US-20260132242-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT ASH2L, ARL1, CARM1 ESR1 2826/4885ESR2 1296/4885TTR 2928/4885
US-20260071103-A1 Anionic Curable Compositions CDH1, ESD, SETD2 ESR1 669/4885ESR2 1338/4885TTR 3907/4885
US-12600856-B2 Resin composition, formed article, and, formed article with hard coat layer ARID2, ASH2L, COL2A1 ESR1 3195/4885ESR2 1945/4885TTR 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.