Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511576 | 0.89 | THRB (0.38) | ALDH1A1TSHRTHRBTP53HIF1A | |
| SCHEMBL8512375 | 0.89 | THRB (0.38) | ALDH1A1TSHRTHRBTP53HIF1A | |
| SCHEMBL9717919 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBTP53HIF1A | |
| SCHEMBL406198 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL11126565 | 0.84 | TSHR (0.39) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL2229640 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRSMN1; SMN2TBXAS1CYP3A4 | |
| SCHEMBL289015 | 0.81 | THRB (0.44) | ALDH1A1TSHRTHRBSMN1; SMN2RAB9A | |
| SCHEMBL33440 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRSMN1; SMN2TBXAS1CYP3A4 | |
| SCHEMBL985177 | 0.81 | TSHR (0.43) | ALDH1A1TSHRTHRBCYP3A4MAPT | |
| SCHEMBL33661 | 0.81 | THRB (0.44) | ALDH1A1TSHRTHRBSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350030-B1 | HYDROPHILIC COPOLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-11-19 | — | — | EP | claimed |
| EP-0350030-A2 | Hydrophilic copolymers, process for their preparation and their use | CESKOSLOVENSKA AKADEMIE VED (CS) | 1990-01-10 | — | — | EP | claimed |
| EP-0350030-B1 | HYDROPHILIC COPOLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-11-19 | — | — | EP | disclosed |
| EP-0350030-A2 | Hydrophilic copolymers, process for their preparation and their use | CESKOSLOVENSKA AKADEMIE VED (CS) | 1990-01-10 | — | — | EP | disclosed |