Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299753 | 0.86 | TDP1 (0.68) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL29777391 | 0.85 | SMN1; SMN2 (0.68) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL975125 | 0.85 | SMN1; SMN2 (0.68) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL29777389 | 0.85 | SMN1; SMN2 (0.68) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL1367306 | 0.84 | TDP1 (0.65) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL28035894 | 0.84 | TDP1 (0.65) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL9844353 | 0.82 | TDP1 (0.63) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL8074225 | 0.80 | TDP1 (0.85) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL21828979 | 0.80 | KDM4E (0.65) | TDP1GAASMN1; SMN2HPGDHTT | |
| SCHEMBL7852351 | 0.80 | TDP1 (0.61) | TDP1GAASMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952253-B | Process for preparing substituted biphenylanilides | BAYER CROPSCIENCE AG | 2013-05-01 | — | — | CN | claimed |
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | claimed |
| CN-101952253-A | Process for preparing substituted biphenylanilides | BAYER CROPSCIENCE AG | 2011-01-19 | — | — | CN | claimed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | claimed |
| EP-2093216-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | claimed |
| CN-102482195-B | Tetraarylborate process for producing substituted biphenyls | BAYER CROPSCIENCE AG | 2015-04-01 | — | — | CN | disclosed |
| EP-2473476-B1 | Tetraarylborate method for producing substituted biphenyls | BAYER IP GMBH (DE) | 2015-01-14 | — | — | EP | disclosed |
| US-8436211-B2 | Tetraarylborate process for the preparation of substituted biphenyls | BAYER CROPSCIENCE AG (DE) | 2013-05-07 | — | — | US | disclosed |
| CN-101952253-B | Process for preparing substituted biphenylanilides | BAYER CROPSCIENCE AG | 2013-05-01 | — | — | CN | disclosed |
| EP-2473476-A1 | TETRAARYLBORATE PROCESS FOR PRODUCING SUBSTITUTED BIPHENYLS | Bayer CropScience AG (DE) | 2012-07-11 | — | — | EP | disclosed |
| CN-102482195-A | Tetraarylborate process for preparing substituted biphenyls | BAYER CROPSCIENCE AG | 2012-05-30 | — | — | CN | disclosed |
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| EP-2257530-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | Bayer CropScience Aktiengesellschaft (DE) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009106234-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | WO | disclosed |
| EP-2093216-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| CN-1845673-A | Pyridylacanilides | BAYER CROPSCIENCE AG (DE) | 2006-10-11 | — | — | CN | disclosed |
| US-20060178513-A1 | Pyridinylanilides | BAYER CROPSCIENCE AG (DE) | 2006-08-10 | — | — | US | disclosed |
| EP-1656020-A2 | PYRIDINYLANILIDES | Bayer CropScience AG (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005004606-A2 | PYRIDINYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178513-A1 | Pyridinylanilides | C3AR1, C5, PADI1 | TDP1 932/4885GAA 2236/4885SMN1; SMN2 3749/4885 |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | DDT, PAH, THOP1 | TDP1 1738/4885GAA 1091/4885SMN1; SMN2 3795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.