Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232409 | 0.84 | CA12 (0.45) | MAOBCYP1A2GAAMAPTRECQL | |
| SCHEMBL4576483 | 0.83 | CA12 (0.44) | MAOBCYP1A2GAAMAPTRECQL | |
| Bromide SCHEMBL9718079 | 0.78 | ATM (0.35) | MAOBKDM4EL3MBTL1MAPK1 | |
| SCHEMBL9293197 | 0.75 | GABRG2 (0.43) | CYP1A2GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL29705684 | 0.75 | MAOB (0.46) | MAOBCYP1A2GAAMAPTRECQL | |
| SCHEMBL3428405 | 0.75 | MAOB (0.46) | MAOBCYP1A2GAAMAPTRECQL | |
| SCHEMBL1877066 | 0.74 | MAOB (0.42) | MAOBCYP1A2GAAMAPTRECQL | |
| SCHEMBL9197307 | 0.74 | IDO1 (0.50) | MAOB | |
| SCHEMBL5352721 | 0.73 | MAOB (0.44) | MAOBCYP1A2GAAMAPTRECQL | |
| SCHEMBL4576012 | 0.73 | CA12 (0.37) | MAOBCYP1A2GAAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5100889-A | Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| US-4883811-A | 7-Oxabicycloheptane imino interphenylene substituted prostaglandin analogs useful in the treatment of thrombotic disease | E. R. SQUIBB & SONS, INC. | 1989-11-28 | — | — | US | disclosed |
| WO-1989000160-A1 | ENANTIOMERICALLY PURE TETRAHYDROFURAN COMPOUNDS AND A METHOD FOR THEIR PREPARATION | ANDERSEN, HENRIK, RASTRUP (DK) | 1989-01-12 | — | — | WO | disclosed |