Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009573 | 0.77 | TAAR1 (0.37) | TAAR1RIPK1CTSSCTSKALDH1A1 | |
| SCHEMBL9566318 | 0.73 | TAAR1 (0.39) | TAAR1RIPK1CTSSCTSKALDH1A1 | |
| SCHEMBL9566191 | 0.71 | TAAR1 (0.37) | TAAR1RIPK1CTSSCTSKIDO1 | |
| SCHEMBL30667522 | 0.70 | TAAR1 (0.41) | TAAR1RIPK1IDO1HTR2AHTR2C | |
| SCHEMBL9566221 | 0.70 | TAAR1 (0.41) | TAAR1RIPK1IDO1HTR2AHTR2C | |
| SCHEMBL6347925 | 0.66 | TAAR1 (0.43) | TAAR1RIPK1IDO1 | |
| SCHEMBL30271106 | 0.66 | TAAR1 (0.43) | TAAR1RIPK1IDO1 | |
| SCHEMBL3408685 | 0.65 | IDO1 (0.53) | TAAR1RIPK1ALDH1A1IDO1 | |
| SCHEMBL5040860 | 0.65 | TAAR1 (0.59) | TAAR1IDO1 | |
| SCHEMBL9175229 | 0.65 | LIPG (0.55) | TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |