Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566318 | 0.80 | TAAR1 (0.39) | TAAR1IDO1RIPK1CTSSCTSK | |
| SCHEMBL9009573 | 0.78 | TAAR1 (0.37) | TAAR1IDO1RIPK1CTSSCTSK | |
| SCHEMBL9718099 | 0.71 | TAAR1 (0.36) | TAAR1IDO1RIPK1CTSSCTSK | |
| SCHEMBL4365156 | 0.69 | TAAR1 (0.54) | TAAR1IDO1 | |
| SCHEMBL9565742 | 0.68 | HTR1A (0.37) | — | |
| SCHEMBL4769399 | 0.68 | APLNR (0.38) | TAAR1IDO1 | |
| SCHEMBL6347925 | 0.67 | TAAR1 (0.43) | TAAR1IDO1RIPK1 | |
| SCHEMBL30271106 | 0.67 | TAAR1 (0.43) | TAAR1IDO1RIPK1 | |
| SCHEMBL30521500 | 0.67 | SLC6A2 (0.61) | TAAR1IDO1 | |
| SCHEMBL623814 | 0.67 | SLC6A2 (0.61) | TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536713-A1 | Oxazole and imidazole derivatives as prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |