SCHEMBL9718199

SCHEMBL9718199

O=c1n(CCO)c(=O)n(CCO)n1CCO

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
THRB P10828 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35878 0.88 PDE4A (0.39) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL6032219 0.85 PDE4A (0.40) HSD17B10KMT2AALDH1A1LMNAPDE4A
Formaldehyde SCHEMBL8709282 0.82 CYP3A4 (0.38) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL30002999 0.80 PDE4A (0.36) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL21163108 0.80 PDE4A (0.36) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL13788796 0.78 PDE4A (0.40) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL2614957 0.78 HTT (0.42) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL2730449 0.78 PDE4A (0.41) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL15428923 0.78 PDE4A (0.35) HSD17B10KMT2AALDH1A1LMNAPDE4A
SCHEMBL11099655 0.78 PTGS1 (0.42) HSD17B10KMT2AALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0043481-B1 SEMIPERMEABLE MEMBRANES BAYER AG (DE) 1984-11-28 EP claimed
US-4383923-A Semipermeable membranes BAYER AKTIENGESELLSCHAFT (DE) 1983-05-17 US claimed
EP-0043481-A2 Semipermeable membranes BAYER AG (DE) 1982-01-13 EP claimed
EP-0173212-B1 ALIPHATIC-AROMATIC POLYAMIDE-IMIDES CONTAINING POLYAMIDE BAYER AG (DE) 1992-03-18 EP disclosed
EP-0136528-B1 PROCESS FOR THE PREPARATION OF POLYAMIDE IMIDES AND THEIR USE BAYER AG (DE) 1991-07-24 EP disclosed
EP-0136526-B1 PROCESS FOR THE PREPARATION OF POLYAMIDE IMIDES BAYER AG (DE) 1991-04-24 EP disclosed
EP-0136527-B1 PROCESS FOR THE PREPARATION OF POLYAMIDE IMIDES BAYER AG (DE) 1991-04-24 EP disclosed
EP-0173207-B1 POLYAMIDE-IMIDES WITH MODIFIED END GROUPS BAYER AG (DE) 1990-09-19 EP disclosed
US-4829140-A Polyamidimides having modified end groups BAYER AKTIENGESELLSCHAFT (DE) 1989-05-09 US disclosed
US-4792590-A Aliphatic-aromatic polyamidimides containing polyamides BAYER AKTEINGESELLSCHAFT (DE) 1988-12-20 US disclosed
US-4707502-A Process for the production of urethane-modified polyisocyanate preparations, the polyisocyanate preparations obtainable by this process and their use in the production of plastics based on polyisocyanates BAYER AKTIENGESELLSCHAFT (DE) 1987-11-17 US disclosed
US-4548970-A Polyamideimides prepared by reacting either lactams or polyamides with polyisocyanates and anhydrides using a lactam as an additive BAYER AKTIENGESELLSCHAFT (DE) 1985-10-22 US disclosed
US-4549006-A Polyamideimides produced from either lactams or polyamides with isocyanates and anhydrides as thermoplasts BAYER AKTIENGESELLSCHAFT (DE) 1985-10-22 US disclosed
US-4546138-A Process for the production of polyamide imides by using a phenol in the workup of the material BAYER AKTIENGESELLSCHAFT (DE) 1985-10-08 US disclosed
EP-0136528-A2 Process for the preparation of polyamide imides and their use BAYER AG (DE) 1985-04-10 EP disclosed
EP-0136526-A2 Process for the preparation of polyamide imides BAYER AG (DE) 1985-04-10 EP disclosed
EP-0136527-A2 Process for the preparation of polyamide imides BAYER AG (DE) 1985-04-10 EP disclosed
EP-0043481-B1 SEMIPERMEABLE MEMBRANES BAYER AG (DE) 1984-11-28 EP disclosed
US-4383923-A Semipermeable membranes BAYER AKTIENGESELLSCHAFT (DE) 1983-05-17 US disclosed
EP-0043481-A2 Semipermeable membranes BAYER AG (DE) 1982-01-13 EP disclosed