Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269874 | 0.82 | GAA (0.48) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL9718272 | 0.81 | CTSS (0.47) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL18460227 | 0.79 | HDAC4 (0.68) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL9718207 | 0.79 | HDAC4 (0.68) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL9425883 | 0.78 | CTSS (0.45) | EPHX1HDAC4HDAC1HDAC6CTSS | |
| SCHEMBL11096628 | 0.75 | HDAC4 (0.51) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL29400626 | 0.75 | HDAC4 (0.51) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL11505471 | 0.75 | HDAC4 (0.51) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL10825239 | 0.72 | EPHX1 (0.43) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL19744864 | 0.72 | EPHX1 (0.43) | EPHX1HDAC4HDAC1HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5100889-A | Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0374952-A2 | 7-Oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E.R. SQUIBB & SONS, INC. (US) | 1990-06-27 | — | — | EP | disclosed |