SCHEMBL24119970

SCHEMBL24119970

O=C1C=CC(=O)N1c1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.63
FAAH O00519 5/20 0.60
HSP90AA1 P07900 4/20 0.55
HTR6 P50406 2/20 0.54
PKM P14618 2/20 0.50
TSHR P16473 1/20 0.50
POLB P06746 1/20 0.49
DDAH1 O94760 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
CCR6 P51684 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9718403 0.92 MGLL (0.68) MGLLFAAHHSP90AA1PKMDDAH1
SCHEMBL331305 0.92 MGLL (0.68) MGLLFAAHHSP90AA1PKMDDAH1
SCHEMBL332770 0.81 MGLL (0.66) MGLLFAAHHSP90AA1PKMDDAH1
SCHEMBL27043314 0.81 MGLL (0.66) MGLLFAAHHSP90AA1PKMDDAH1
Benzenesulfonamide SCHEMBL27874390 0.79 MGLL (0.67) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL8920586 0.79 MGLL (1.00) MGLLFAAHHSP90AA1PKMDDAH1
SCHEMBL18713 0.79 MGLL (1.00) MGLLFAAHHSP90AA1PKMDDAH1
Benzene SCHEMBL28088808 0.79 MGLL (1.00) MGLLFAAHHSP90AA1PKMDDAH1
SCHEMBL4632649 0.78 KMT2A (0.61) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL30408507 0.77 MGLL (0.67) MGLLFAAHHSP90AA1HTR6PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3632941-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2023-08-23 EP claimed
EP-3632941-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2023-08-23 EP disclosed
US-20210395420-A1 RESIN COMPOSITION CUBICURE GMBH (AT) 2021-12-23 US disclosed