Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.44 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283331 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL2279553 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL2983597 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL2283336 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL2279558 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL2283589 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL2981700 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL17231345 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL9442151 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 | |
| SCHEMBL2283596 | 1.00 | NAAA (0.58) | NAAAHTR2CNPSR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180311316-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | ADOCIA (FR) | 2018-11-01 | — | — | US | claimed |
| US-20170182131-A9 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | ADOCIA (FR) | 2017-06-29 | — | — | US | claimed |
| EP-2741765-B9 | INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN | ADOCIA (FR) | 2016-09-28 | — | — | EP | claimed |
| EP-2741765-B1 | INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN | ADOCIA (FR) | 2016-03-30 | — | — | EP | claimed |
| US-20150250858-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | ADOCIA (FR) | 2015-09-10 | — | — | US | claimed |
| US-9089476-B2 | Injectable solution at pH 7 comprising at least one basal insulin whose PI is between 5.8 and 8.5 | ADOCIA (FR) | 2015-07-28 | — | — | US | claimed |
| CN-103889442-A | Injectable solution of at least one basal insulin | ADOCIA | 2014-06-25 | — | — | CN | claimed |
| US-20130065826-A1 | Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 | ADOCIA (FR) | 2013-03-14 | — | — | US | claimed |
| US-20120309680-A1 | Functionalized oligosaccharides | ADOCIA (FR) | 2012-12-06 | — | — | US | claimed |
| US-10449256-B2 | Injectable solution at pH 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer | ADOCIA (FR) | 2019-10-22 | — | — | US | disclosed |
| US-20180311316-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | ADOCIA (FR) | 2018-11-01 | — | — | US | disclosed |
| US-20180169249-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANIONIC POLYMER | ADOCIA (FR) | 2018-06-21 | — | — | US | disclosed |
| US-20170182131-A9 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | ADOCIA (FR) | 2017-06-29 | — | — | US | disclosed |
| US-20150314003-A2 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANIONIC POLYMER | ADOCIA (FR) | 2015-11-05 | — | — | US | disclosed |
| US-9018190-B2 | Functionalized oligosaccharides | ADOCIA (FR) | 2015-04-28 | — | — | US | disclosed |
| US-20140249079-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANONIC POLYMER | ADOCIA (FR) | 2014-09-04 | — | — | US | disclosed |
| CN-103889442-A | Injectable solution of at least one basal insulin | ADOCIA | 2014-06-25 | — | — | CN | disclosed |
| US-20130065826-A1 | Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 | ADOCIA (FR) | 2013-03-14 | — | — | US | disclosed |
| US-20120309680-A1 | Functionalized oligosaccharides | ADOCIA (FR) | 2012-12-06 | — | — | US | disclosed |
| US-5139807-A | Replacements for fats and oils in foods | NABISCO, INC. (US) | 1992-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170182131-A9 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | IAPP, IGFBP5, INSR | NAAA 3588/4885HTR2C 3723/4885NPSR1 3279/4885 |
| US-20180311316-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | IAPP, IGFBP5, INSR | NAAA 3588/4885HTR2C 3723/4885NPSR1 3279/4885 |
| US-20150250858-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 | IAPP, IGFBP5, INSR | NAAA 3588/4885HTR2C 3723/4885NPSR1 3279/4885 |
| US-20180169249-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANIONIC POLYMER | IAPP, IGFBP5, IDE | NAAA 2008/4885HTR2C 3803/4885NPSR1 1823/4885 |
| US-20120309680-A1 | Functionalized oligosaccharides | OSTC, STT3A, DDOST | NAAA 4138/4885HTR2C 4045/4885NPSR1 152/4885 |
| US-10449256-B2 | Injectable solution at pH 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer | IAPP, IGFBP5, IDE | NAAA 2008/4885HTR2C 3803/4885NPSR1 1823/4885 |
| US-20150314003-A2 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANIONIC POLYMER | IAPP, IGFBP5, IDE | NAAA 2008/4885HTR2C 3803/4885NPSR1 1823/4885 |
| US-20130065826-A1 | Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 | IAPP, IGFBP5, INSR | NAAA 3588/4885HTR2C 3723/4885NPSR1 3279/4885 |
| US-20140249079-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANONIC POLYMER | IAPP, IGFBP5, IDE | NAAA 1259/4885HTR2C 4479/4885NPSR1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.