Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245264 | 0.79 | KMT2A (0.43) | KMT2ANPSR1L3MBTL1MAPTPOLB | |
| SCHEMBL9004640 | 0.74 | KMT2A (0.40) | KMT2ANPSR1L3MBTL1MAPTPOLB | |
| SCHEMBL9793654 | 0.74 | KMT2A (0.40) | KMT2ANPSR1L3MBTL1MAPTPOLB | |
| SCHEMBL2404814 | 0.70 | TSHR (0.34) | KMT2ANPSR1L3MBTL1MAPTPOLB | |
| SCHEMBL10561225 | 0.70 | KMT2A (0.40) | KMT2ANPSR1L3MBTL1MAPTPOLB | |
| SCHEMBL9052323 | 0.70 | LMNA (0.44) | KMT2AL3MBTL1MAPTPOLBLMNA | |
| Hydrochloric Acid SCHEMBL9053050 | 0.68 | LMNA (0.43) | KMT2AL3MBTL1MAPTPOLBLMNA | |
| SCHEMBL9718676 | 0.68 | LMNA (0.46) | KMT2AL3MBTL1MAPTPOLBLMNA | |
| SCHEMBL9004824 | 0.67 | KMT2A (0.46) | KMT2ANPSR1L3MBTL1MAPTPOLB | |
| SCHEMBL9793604 | 0.67 | KMT2A (0.46) | KMT2ANPSR1L3MBTL1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0108037-B1 | PROPIOPHENONE DERIVATIVES AS PHOTOINITIATORS IN THE PHOTOPOLYMERIZATION | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0108037-A2 | Propiophenone derivatives as photoinitiators in the photopolymerization | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |