Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.40 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.40 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004824 | 1.00 | KMT2A (0.46) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL9004736 | 0.82 | ALDH1A1 (0.37) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL9316339 | 0.82 | ALDH1A1 (0.37) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL11252173 | 0.81 | LMNA (0.38) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL10528850 | 0.78 | CYP2C19 (0.45) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL9718676 | 0.75 | LMNA (0.46) | KMT2AMEN1CYP2C19NPC1RAB9A | |
| SCHEMBL13244703 | 0.74 | MAPK1 (0.43) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL9314659 | 0.72 | CES2 (0.38) | ALDH1A1 | |
| SCHEMBL1847228 | 0.72 | MAPK1 (0.73) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL11268200 | 0.71 | MAPK1 (0.58) | KMT2AMEN1CYP2C19MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068371-A | Photoinitiators for polymerization | CIBA-GEIGY CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |
| US-5034307-A | Photopolymerization of ethylenically unsaturated substrates | CIBA-GEIGY CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| US-4970136-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-13 | — | — | US | disclosed |
| US-4963470-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| US-4857654-A | Titanocenes and their use | CIBA-GEIGY CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |