Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004904 | 0.78 | LMNA (0.36) | LMNANPSR1POLBGAAMAPK1 | |
| SCHEMBL9314611 | 0.77 | ALDH1A1 (0.36) | LMNACETPNPSR1POLBGAA | |
| SCHEMBL9004647 | 0.77 | ALDH1A1 (0.36) | LMNACETPNPSR1POLBGAA | |
| SCHEMBL9718669 | 0.73 | AKR1C1 (0.39) | LMNANPSR1POLBGAAMAPK1 | |
| SCHEMBL31389002 | 0.68 | LMNA (0.35) | LMNAPOLBGAAALDH1A1CYP1A2 | |
| SCHEMBL9004751 | 0.65 | LMNA (0.40) | LMNAPOLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9803438 | 0.65 | LMNA (0.40) | LMNACETPNPSR1GAAALDH1A1 | |
| SCHEMBL21077437 | 0.65 | CETP (0.50) | LMNACETPNPSR1GAAALDH1A1 | |
| SCHEMBL14421361 | 0.65 | LMNA (0.46) | LMNACETPNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL9718676 | 0.65 | LMNA (0.46) | LMNAPOLBALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0108037-B1 | PROPIOPHENONE DERIVATIVES AS PHOTOINITIATORS IN THE PHOTOPOLYMERIZATION | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0108037-A2 | Propiophenone derivatives as photoinitiators in the photopolymerization | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |