Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10528811 | 0.81 | GLS (0.42) | LMNAMEN1KMT2ACYP1A2SLC6A2 | |
| SCHEMBL14453309 | 0.79 | LMNA (0.35) | AKR1C1LMNAALDH1A1OPRM1TSHR | |
| SCHEMBL9004647 | 0.78 | ALDH1A1 (0.36) | LMNAMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9314611 | 0.78 | ALDH1A1 (0.36) | LMNAMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8765171 | 0.78 | LMNA (0.41) | AKR1C1HDAC4LMNAMEN1KMT2A | |
| SCHEMBL11611329 | 0.77 | LMNA (0.36) | LMNAMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL9004904 | 0.77 | LMNA (0.36) | AKR1C1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL11491382 | 0.73 | LMNA (0.38) | LMNAKMT2ACYP1A2SLC6A2SLC6A4 | |
| SCHEMBL9718810 | 0.73 | LMNA (0.34) | AKR1C1LMNAKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL6326779 | 0.71 | LMNA (0.36) | AKR1C1LMNASMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0108037-A2 | Propiophenone derivatives as photoinitiators in the photopolymerization | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |