Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.32 |
| ▸ | MAOA | P21397 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107121 | 0.77 | KDM1A (0.42) | BACE1BACE2KDM1AKMT2A | |
| SCHEMBL2846013 | 0.68 | BACE1 (0.42) | BACE1BACE2MAOAMAOBREN | |
| SCHEMBL14077810 | 0.63 | BACE1 (0.46) | BACE1BACE2RENAPPPOLB | |
| SCHEMBL7551055 | 0.62 | PNMT (0.39) | KDM1AMAOAMAOBPNMT | |
| SCHEMBL31500571 | 0.62 | BACE1 (0.43) | BACE1BACE2KDM1AMAOAMAOB | |
| SCHEMBL14656128 | 0.60 | BACE1 (0.42) | BACE1BACE2MAOAMAOBREN | |
| SCHEMBL10650069 | 0.60 | PNMT (0.34) | KDM1AMAOAMAOBPNMT | |
| SCHEMBL9718904 | 0.59 | BACE1 (0.37) | BACE1BACE2KDM1AMAOAMAOB | |
| SCHEMBL28454137 | 0.59 | BACE1 (0.37) | BACE1BACE2KDM1AMAOAMAOB | |
| SCHEMBL5536641 | 0.58 | BACE1 (0.33) | BACE1BACE2RENAPPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112926-A | Improved hardness, toughness and drilling properties | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1992-05-12 | — | — | US | disclosed |