Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446169 | 0.69 | CD44 (0.37) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL5607855 | 0.68 | BACE1 (0.33) | BACE1BACE2CYP3A4ALOX15CASP1 | |
| SCHEMBL7551055 | 0.61 | PNMT (0.39) | — | |
| SCHEMBL2224688 | 0.59 | BACE1 (0.34) | BACE1BACE2RENAPP | |
| Hydrochloric Acid SCHEMBL14576582 | 0.58 | BACE1 (0.33) | BACE1BACE2RENAPP | |
| Hydrochloric Acid SCHEMBL21192543 | 0.58 | BACE1 (0.33) | BACE1BACE2RENAPP | |
| SCHEMBL9718903 | 0.58 | BACE1 (0.41) | BACE1BACE2RENAPPLMNA | |
| SCHEMBL11264366 | 0.58 | LMNA (0.38) | BACE1BACE2RENAPPKDM4E | |
| SCHEMBL4266501 | 0.58 | MAOA (0.33) | BACE1BACE2RENAPP | |
| SCHEMBL22003326 | 0.57 | CYP3A4 (0.91) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646234-A | AROMATIC POLYAMIDES | HOECHST AG (DE) | 1997-07-08 | — | — | US | claimed |
| EP-0695776-A2 | Process for the preparation of fibers or films, and fibers or films obtained therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | claimed |
| WO-2007094561-A1 | HIGH MOLOCULAR ELECTROLYTE MEMBRANE FOR FUEL CELL, AND MEMBRANE-ELECTRODE ASSEMBLY THEREBY, FUEL CELL | CHEIL INDUSTRIES INC. (KR) | 2007-08-23 | — | — | WO | disclosed |
| EP-0718425-B1 | Two-component intermingled sewing threads from aramid filaments, their production process and their use | HOECHST TREVIRA GMBH & CO KG (DE) | 1999-06-09 | — | — | EP | disclosed |
| US-5646234-A | AROMATIC POLYAMIDES | HOECHST AG (DE) | 1997-07-08 | — | — | US | disclosed |
| US-5645935-A | Two-component loop yarns comprising aramid filaments, manufacture thereof and use thereof | HOECHST TREVIRA GMBH & CO. KG (DE) | 1997-07-08 | — | — | US | disclosed |
| US-5571891-A | FROM 2-AMINOPHENYL-SUBSTITUTED AMINOBENZIMIDAZOLES, AMINOBENZOTHIAZOLES OR AMINOBENZOXAZOLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |
| EP-0718425-A1 | Two-component intermingled sewing threads from aramid filaments, their production process and their use | Hoechst Trevira GmbH & Co. KG (DE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0695776-A2 | Process for the preparation of fibers or films, and fibers or films obtained therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |
| EP-0678539-A2 | Aromatic copolyamides, process for their preparation, moulded articles and their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-25 | — | — | EP | disclosed |