Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 11/20 | 0.32 |
| ▸ | MAOA | P21397 | 10/20 | 0.32 |
| ▸ | KDM1A | O60341 | 6/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541922 | 0.73 | — | — | |
| SCHEMBL7551055 | 0.72 | PNMT (0.39) | PNMTMAOBMAOAKDM1ATAAR1 | |
| SCHEMBL11222671 | 0.70 | MEN1 (0.30) | — | |
| SCHEMBL11769770 | 0.64 | MAPT (0.39) | MAOB | |
| SCHEMBL9718903 | 0.60 | BACE1 (0.41) | PNMTMAOBMAOAKDM1A | |
| SCHEMBL9718904 | 0.60 | BACE1 (0.37) | PNMTMAOBMAOAKDM1A | |
| SCHEMBL1009890 | 0.60 | MAOA (0.38) | MAOBMAOAKDM1A | |
| SCHEMBL4654991 | 0.59 | — | — | |
| SCHEMBL10928766 | 0.59 | OPRM1 (0.36) | PNMTMAOBMAOATAAR1 | |
| SCHEMBL9877949 | 0.58 | PNMT (0.35) | PNMTMAOBMAOAKDM1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121490-B1 | Substituted 6-aryl-1,2,4-triazolo[4,3-b]pyridazines, their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-02 | — | — | EP | disclosed |