Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexaethylene Glycol SCHEMBL9719257 | 1.00 | HSD17B10 (0.34) | HSD17B10TDP1 | |
| Fumaric Acid SCHEMBL9719211 | 1.00 | HSD17B10 (0.34) | HSD17B10TDP1 | |
| SCHEMBL9719207 | 0.93 | HCAR2 (0.38) | HSD17B10TDP1 | |
| Maleic Acid SCHEMBL9719226 | 0.87 | HSD17B10 (0.44) | HSD17B10TDP1 | |
| Fumaric Acid SCHEMBL9719243 | 0.87 | HSD17B10 (0.44) | HSD17B10TDP1 | |
| Fumaric Acid SCHEMBL9719235 | 0.87 | HSD17B10 (0.44) | HSD17B10TDP1 | |
| Fumaric Acid SCHEMBL9719239 | 0.87 | HSD17B10 (0.44) | HSD17B10TDP1 | |
| Acrylic Acid SCHEMBL6667897 | 0.82 | HSD17B10 (0.42) | HSD17B10TDP1 | |
| Acrylic Acid SCHEMBL6423307 | 0.79 | HSD17B10 (0.45) | HSD17B10TDP1 | |
| Maleic Acid SCHEMBL9171448 | 0.79 | CA1 (0.44) | HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162402-A | For concrete containing a polymeric composition | SANDOZ LTD. (CH) | 1992-11-10 | — | — | US | claimed |
| US-5162402-A | For concrete containing a polymeric composition | SANDOZ LTD. (CH) | 1992-11-10 | — | — | US | disclosed |